Material Safety Data Sheet
n-Butyric Anhydride, 98%

ACC# 96914
Section 1 - Chemical Product and Company Identification

MSDS Name: n-Butyric Anhydride, 98%
Catalog Numbers: AC108120000, AC108120010, AC108120025, AC9974411, XXAC10812-37
Synonyms:
Butanoic Anhydride; Butyryl Oxide
Company Identification:

              Fisher Scientific
              1 Reagent Lane
              Fair Lawn, NJ 07410
For information, call:
201-796-7100
Emergency Number:
201-796-7100
For CHEMTREC assistance, call:
800-424-9300
For International CHEMTREC assistance, call:
703-527-3887

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
106-31-0 N-BUTYRIC ANHYDRIDE 98 203-383-4

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: slight clear yellow liquid. Flash Point: 87 deg C.
Danger! Corrosive. Causes eye and skin burns. Causes digestive and respiratory tract burns. Combustible liquid and vapor. Moisture sensitive.
Target Organs: None known.


Potential Health Effects
Eye: Causes eye burns.
Skin: Causes skin burns.
Ingestion: Causes gastrointestinal tract burns.
Inhalation: Causes chemical burns to the respiratory tract. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema.
Chronic: Not available.

Section 4 - First Aid Measures


Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid imme diately.
Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician: Treat symptomatically.

Section 5 - Fire Fighting Measures


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Containers may explode in the heat of a fire. Combustible liquid. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media: Do NOT use water directly on fire. Use water spray to cool fire-exposed containers. For small fires, use dry chemical, sand, water spray, or foam. Do NOT get water inside containers. For large fires, use water spray, fog or alcohol-resistant foam.
Flash Point: 87 deg C ( 188.60 deg F)
Autoignition Temperature: 279 deg C ( 534.20 deg F)
Explosion Limits, Lower:0.9
Upper: 5.8
NFPA Rating: 3 - health, 2 - flammability, 1 - instability

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Remove all sources of ignition. Use a spark-proof tool. Do not get water inside containers.

Section 7 - Handling and Storage


Handling: Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Use only in a chemical fume hood. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage: Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container. Corrosives area. Store protected from moisture.

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Use adequate ventilation to keep airborne concentrations low.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
N-BUTYRIC ANHYDRIDE none listed none listed none listed

OSHA Vacated PELs: N-BUTYRIC ANHYDRIDE: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - Physical and Chemical Properties


Physical State: Liquid
Appearance: slight clear yellow
Odor: Stench
pH: Not available.
Vapor Pressure: 0.3 mm Hg @ 20 deg C
Vapor Density: 5.45
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 199 deg C @ 760.00mnHg
Freezing/Melting Point:-66 deg C
Decomposition Temperature:Not available.
Solubility: Soluble.
Specific Gravity/Density:.9670g/cm3
Molecular Formula:C8H14O3
Molecular Weight:158.20

Section 10 - Stability and Reactivity


Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Incompatible materials, exposure to moist air or water.
Incompatibilities with Other Materials: Strong oxidizing agents, acids, bases, reducing agents, alcohols.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - Toxicological Information


RTECS#:      
CAS# 106-31-0: ET7090000
LD50/LC50:
CAS# 106-31-0:
     Oral, rat: LD50 = 8790 mg/kg;
.

Carcinogenicity:
CAS# 106-31-0: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: No information available.
Teratogenicity: No information available.
Reproductive Effects: No information available.
Mutagenicity: No information available.
Neurotoxicity: No information available.
Other Studies:

Section 12 - Ecological Information

No information available.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT Canada TDG
Shipping Name: BUTYRIC ANHYDRIDE BUTYRIC ANHYDRIDE
Hazard Class: 8 8
UN Number: UN2739 UN2739
Packing Group: III III

Section 15 - Regulatory Information

US FEDERAL

TSCA
     CAS# 106-31-0 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
SARA Codes
     CAS # 106-31-0: immediate, fire.
Section 313      No chemicals are reportable under Section 313.
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 106-31-0 can be found on the following state right to know lists: New Jersey.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations

European Labeling in Accordance with EC Directives
Hazard Symbols:
     C
Risk Phrases:

     R 34 Causes burns.

Safety Phrases:

     S 25 Avoid contact with eyes.
     S 26 In case of contact with eyes, rinse immediately with plenty of
     water and seek medical advice.
     S 36/37/39 Wear suitable protective clothing, gloves and eye/face pr
     otection.
     S 45 In case of accident or if you feel unwell, seek medical advice
     immediately (show the label where possible).

WGK (Water Danger/Protection)

     CAS# 106-31-0: 1
Canada - DSL/NDSL
     CAS# 106-31-0 is listed on Canada's DSL List.
Canada - WHMIS
     not available.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
     CAS# 106-31-0 is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 1/05/1998
Revision #3 Date: 10/03/2005

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.